Friday, September 20, 2019

Monoenoic fatty acid: palmitoleic acid

The two most common omega-7 fatty acids in nature are palmitoleic acid and vaccenic acid. Palmitoleic acid is a monounsaturated fatty acid (MUFA).

 Palmitoleic acid (16:1ω -7) occurs widely in animals, plants and microorganisms, and is a major component in some seed oils. Macadamia oil (Macadamia integrifolia) and sea buckthorn oil (Hippophaë rhamnoides) are botanical sources with high concentrations, containing 17% and 19% (minimum) to 29% (maximum) of palmitoleic acid, respectively. Palmitoleic acid has the formula CH3(CH2)5CH=CH(CH2)7COOH.

The MUFA palmitoleic acid or palmitoleate (16:1n–7 or 16:1D9) has received a lot of attention in recent years, even though its metabolism was described in the 1960s.

Palmitoleate can be found as a cis (16:1 c9) or a trans (16:1 t9) isomer. The cis isoform (cis-palmitoleate) has been associated with increased insulin sensitivity and decreased lipid accumulation in the liver.
Monoenoic fatty acid: palmitoleic acid
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