Monday, April 20, 2015

Etiology of osteoporosis

Osteoporosis is the thinning of bone tissue and loss of bone density over time. Osteoporosis results when too much bone resorption occurs, too little formation exists, or a combination of both co-exists.

A major cause of osteoporoses is less than optimal bone growth during childhood and adolescence, resulting in failure to reach optimal peak bone mass.

Thus, peak bone mass attained early in life is one of the major important factors affecting the risk of osteoporosis.

Other common causes of osteoporosis include aging, menopause, endocrine disorders, metabolic disorders, malnutrition, malabsorption, and malignancy. Menopause and ageing are the most common causes of osteoporosis.

Endocrine, metabolic and nutritional disorders are more likely to cause osteomalacia, which radiographically resembles osteoporosis but is metabolically and clinically different from osteoporosis.

Increased bone resorption results from estrogen deficiency associated the menopause in normal women also one of the major cause of osteoporosis.

Males with low levels of testosterone are also more prone. The use of tobacco and a family history of osteoporosis also increase the risk.
Etiology of osteoporosis

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